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Use of Computational Biochemistry for Elucidating Molecular Mechanisms of Nitric Oxide Synthase
Nitric oxide (NO) is an essential signaling molecule in the regulation of multiple cellular processes. It is endogenously synthesized by NO synthase (NOS) as the product of L-arginine oxidation to L-citrulline, requiring NADPH, molecular oxygen, and a pterin cofactor. Two NOS isoforms are constituti...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451115/ https://www.ncbi.nlm.nih.gov/pubmed/30996821 http://dx.doi.org/10.1016/j.csbj.2019.03.011 |