Use of Computational Biochemistry for Elucidating Molecular Mechanisms of Nitric Oxide Synthase

Nitric oxide (NO) is an essential signaling molecule in the regulation of multiple cellular processes. It is endogenously synthesized by NO synthase (NOS) as the product of L-arginine oxidation to L-citrulline, requiring NADPH, molecular oxygen, and a pterin cofactor. Two NOS isoforms are constituti...

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Detalles Bibliográficos
Autores principales: Bignon, Emmanuelle, Rizza, Salvatore, Filomeni, Giuseppe, Papaleo, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2019
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451115/
https://www.ncbi.nlm.nih.gov/pubmed/30996821
http://dx.doi.org/10.1016/j.csbj.2019.03.011

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