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The G3-U70-independent tRNA recognition by human mitochondrial alanyl-tRNA synthetase

Alanyl-tRNA synthetases (AlaRSs) from three domains of life predominantly rely on a single wobble base pair, G3-U70, of tRNA(Ala) as a major determinant. However, this base pair is divergent in human mitochondrial tRNA(Ala), but instead with a translocated G5-U68. How human mitochondrial AlaRS (hmtA...

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Detalles Bibliográficos
Autores principales: Zeng, Qi-Yu, Peng, Gui-Xin, Li, Guang, Zhou, Jing-Bo, Zheng, Wen-Qiang, Xue, Mei-Qin, Wang, En-Duo, Zhou, Xiao-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451123/
https://www.ncbi.nlm.nih.gov/pubmed/30952159
http://dx.doi.org/10.1093/nar/gkz078