Cargando…

Understanding the role of intermolecular interactions between lissoclimides and the eukaryotic ribosome

Natural products that target the eukaryotic ribosome are promising therapeutics to treat a variety of cancers. It is therefore essential to determine their molecular mechanism of action to fully understand their mode of interaction with the target and to inform the development of new synthetic compo...

Descripción completa

Detalles Bibliográficos
Autores principales: Pellegrino, Simone, Meyer, Mélanie, Könst, Zef A, Holm, Mikael, Voora, Vamsee K, Kashinskaya, Daniya, Zanette, Camila, Mobley, David L, Yusupova, Gulnara, Vanderwal, Chris D, Blanchard, Scott C, Yusupov, Marat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451132/
https://www.ncbi.nlm.nih.gov/pubmed/30759226
http://dx.doi.org/10.1093/nar/gkz053