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Fosb Induction in Nucleus Accumbens by Cocaine Is Regulated by E2F3a

The transcription factor ΔFosB has been proposed as a molecular switch for the transition from casual, volitional drug use into a chronically addicted state, but the upstream regulatory mechanisms governing ΔFosB expression are incompletely understood. In this study, we find a novel regulatory role...

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Detalles Bibliográficos
Autores principales: Cates, Hannah M., Lardner, Casey K., Bagot, Rosemary C., Neve, Rachael L., Nestler, Eric J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451158/
https://www.ncbi.nlm.nih.gov/pubmed/30963104
http://dx.doi.org/10.1523/ENEURO.0325-18.2019