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Comparative analysis of the chicken IFITM locus by targeted genome sequencing reveals evolution of the locus and positive selection in IFITM1 and IFITM3

BACKGROUND: The interferon-induced transmembrane (IFITM) protein family comprises a class of restriction factors widely characterised in humans for their potent antiviral activity. Their biological activity is well documented in several animal species, but their genetic variation and biological mech...

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Detalles Bibliográficos
Autores principales: Bassano, Irene, Ong, Swee Hoe, Sanz-Hernandez, Maximo, Vinkler, Michal, Kebede, Adebabay, Hanotte, Olivier, Onuigbo, Ebele, Fife, Mark, Kellam, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451222/
https://www.ncbi.nlm.nih.gov/pubmed/30952207
http://dx.doi.org/10.1186/s12864-019-5621-5