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Intratumor heterogeneity index of breast carcinomas based on DNA methylation profiles
BACKGROUND: Cancer cells evolve and constitute heterogeneous populations that fluctuate in space and time and are subjected to selection generating intratumor heterogeneity. This phenomenon is determined by the acquisition of genetic/epigenetic alterations and their selection over time which has cli...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451266/ https://www.ncbi.nlm.nih.gov/pubmed/30953488 http://dx.doi.org/10.1186/s12885-019-5550-3 |