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Intratumor heterogeneity index of breast carcinomas based on DNA methylation profiles

BACKGROUND: Cancer cells evolve and constitute heterogeneous populations that fluctuate in space and time and are subjected to selection generating intratumor heterogeneity. This phenomenon is determined by the acquisition of genetic/epigenetic alterations and their selection over time which has cli...

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Detalles Bibliográficos
Autores principales: Campoy, Emanuel M., Branham, María T., Mayorga, Luis S., Roqué, María
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451266/
https://www.ncbi.nlm.nih.gov/pubmed/30953488
http://dx.doi.org/10.1186/s12885-019-5550-3