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Defined conditions for propagation and manipulation of mouse embryonic stem cells

The power of mouse embryonic stem (ES) cells to colonise the developing embryo has revolutionised mammalian developmental genetics and stem cell research. This power is vulnerable, however, to the cell culture environment, deficiencies in which can lead to cellular heterogeneity, adaptive phenotypes...

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Detalles Bibliográficos
Autores principales: Mulas, Carla, Kalkan, Tüzer, von Meyenn, Ferdinand, Leitch, Harry G., Nichols, Jennifer, Smith, Austin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451320/
https://www.ncbi.nlm.nih.gov/pubmed/30914406
http://dx.doi.org/10.1242/dev.173146