Constitutive STAT5 activation regulates Paneth and Paneth-like cells to control Clostridium difficile colitis

Clostridium difficile impairs Paneth cells, driving intestinal inflammation that exaggerates colitis. Besides secreting bactericidal products to restrain C. difficile, Paneth cells act as guardians that constitute a niche for intestinal epithelial stem cell (IESC) regeneration. However, how IESCs ar...

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Detalles Bibliográficos
Autores principales: Liu, Ruixue, Moriggl, Richard, Zhang, Dongsheng, Li, Haifeng, Karns, Rebekah, Ruan, Hai-Bin, Niu, Haitao, Mayhew, Christopher, Watson, Carey, Bangar, Hansraj, Cha, Sang-wook, Haslam, David, Zhang, Tongli, Gilbert, Shila, Li, Na, Helmrath, Michael, Wells, James, Denson, Lee, Han, Xiaonan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451325/
https://www.ncbi.nlm.nih.gov/pubmed/30948494
http://dx.doi.org/10.26508/lsa.201900296

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451325/
https://www.ncbi.nlm.nih.gov/pubmed/30948494
http://dx.doi.org/10.26508/lsa.201900296

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