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Mutation of microphthalmia-associated transcription factor (mitf) in zebrafish sensitizes for glomerulopathy

Different glomerular diseases that affect podocyte homeostasis can clinically present as nephrotic syndrome with massive proteinuria, hypoalbuminemia, hyperlipidemia and edema. Up to now, no drugs that specifically target the actin cytoskeleton of podocytes are on the market and model systems for li...

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Detalles Bibliográficos
Autores principales: Müller-Deile, Janina, Schenk, Heiko, Niggemann, Philipp, Bolaños-Palmieri, Patricia, Teng, Beina, Higgs, Alysha, Staggs, Lynne, Haller, Hermann, Schroder, Patricia, Schiffer, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451330/
https://www.ncbi.nlm.nih.gov/pubmed/30718228
http://dx.doi.org/10.1242/bio.040253