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Jagged1 protein processing in the developing mammalian lens

Notch signaling regulates a multitude of cellular processes. During ocular lens development this pathway is required for lens progenitor growth, differentiation and maintenance of the transition zone. After ligand-receptor binding, the receptor proteins are processed, first by ADAM proteases, then b...

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Detalles Bibliográficos
Autores principales: Azimi, Mina, Brown, Nadean L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451331/
https://www.ncbi.nlm.nih.gov/pubmed/30890522
http://dx.doi.org/10.1242/bio.041095