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The 1ALCTL and 1BLCTL isoforms of Arg/Abl2 induce fibroblast activation and extra cellular matrix remodelling differently

The fibrotic tissue and the stroma adjacent to cancer cells are characterised by the presence of activated fibroblasts (myofibroblasts) which play a role in creating a supportive tissue characterised by abundant extracellular matrix (ECM) secretion. The myofibroblasts remodel this tissue through sec...

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Detalles Bibliográficos
Autores principales: Torsello, Barbara, De Marco, Sofia, Bombelli, Silvia, Chisci, Elisa, Cassina, Valeria, Corti, Roberta, Bernasconi, Davide, Giovannoni, Roberto, Bianchi, Cristina, Perego, Roberto A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451347/
https://www.ncbi.nlm.nih.gov/pubmed/30837227
http://dx.doi.org/10.1242/bio.038554