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The molecular, cellular and pathophysiological roles of iRhom pseudoproteases

iRhom proteins are catalytically inactive relatives of rhomboid intramembrane proteases. There is a rapidly growing body of evidence that these pseudoenzymes have a central function in regulating inflammatory and growth factor signalling and consequent roles in many diseases. iRhom pseudoproteases h...

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Detalles Bibliográficos
Autores principales: Dulloo, Iqbal, Muliyil, Sonia, Freeman, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451368/
https://www.ncbi.nlm.nih.gov/pubmed/30890028
http://dx.doi.org/10.1098/rsob.190003