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The molecular, cellular and pathophysiological roles of iRhom pseudoproteases
iRhom proteins are catalytically inactive relatives of rhomboid intramembrane proteases. There is a rapidly growing body of evidence that these pseudoenzymes have a central function in regulating inflammatory and growth factor signalling and consequent roles in many diseases. iRhom pseudoproteases h...
Autores principales: | Dulloo, Iqbal, Muliyil, Sonia, Freeman, Matthew |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451368/ https://www.ncbi.nlm.nih.gov/pubmed/30890028 http://dx.doi.org/10.1098/rsob.190003 |
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