The zebrafish orthologue of the human hepatocerebral disease gene MPV17 plays pleiotropic roles in mitochondria

Mitochondrial DNA depletion syndromes (MDS) are a group of rare autosomal recessive disorders with early onset and no cure available. MDS are caused by mutations in nuclear genes involved in mitochondrial DNA (mtDNA) maintenance, and characterized by both a strong reduction in mtDNA content and seve...

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Detalles Bibliográficos
Autores principales: Martorano, Laura, Peron, Margherita, Laquatra, Claudio, Lidron, Elisa, Facchinello, Nicola, Meneghetti, Giacomo, Tiso, Natascia, Rasola, Andrea, Ghezzi, Daniele, Argenton, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451431/
https://www.ncbi.nlm.nih.gov/pubmed/30833296
http://dx.doi.org/10.1242/dmm.037226

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451431/
https://www.ncbi.nlm.nih.gov/pubmed/30833296
http://dx.doi.org/10.1242/dmm.037226

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