Reverse genetic screen reveals that Il34 facilitates yolk sac macrophage distribution and seeding of the brain

Microglia are brain-resident macrophages, which have specialized functions important in brain development and in disease. They colonize the brain in early embryonic stages, but few factors that drive the migration of yolk sac macrophages (YSMs) into the embryonic brain, or regulate their acquisition...

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Detalles Bibliográficos
Autores principales: Kuil, Laura E., Oosterhof, Nynke, Geurts, Samuël N., van der Linde, Herma C., Meijering, Erik, van Ham, Tjakko J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451432/
https://www.ncbi.nlm.nih.gov/pubmed/30765415
http://dx.doi.org/10.1242/dmm.037762

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451432/
https://www.ncbi.nlm.nih.gov/pubmed/30765415
http://dx.doi.org/10.1242/dmm.037762

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