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Reverse genetic screen reveals that Il34 facilitates yolk sac macrophage distribution and seeding of the brain
Microglia are brain-resident macrophages, which have specialized functions important in brain development and in disease. They colonize the brain in early embryonic stages, but few factors that drive the migration of yolk sac macrophages (YSMs) into the embryonic brain, or regulate their acquisition...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Company of Biologists Ltd
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451432/ https://www.ncbi.nlm.nih.gov/pubmed/30765415 http://dx.doi.org/10.1242/dmm.037762 |