BCL-3 promotes a cancer stem cell phenotype by enhancing β-catenin signalling in colorectal tumour cells

To decrease bowel cancer incidence and improve survival, we need to understand the mechanisms that drive tumorigenesis. Recently, B-cell lymphoma 3 (BCL-3; a key regulator of NF-κB signalling) has been recognised as an important oncogenic player in solid tumours. Although reported to be overexpresse...

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Detalles Bibliográficos
Autores principales: Legge, Danny N., Shephard, Alex P., Collard, Tracey J., Greenhough, Alexander, Chambers, Adam C., Clarkson, Richard W., Paraskeva, Christos, Williams, Ann C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451435/
https://www.ncbi.nlm.nih.gov/pubmed/30792270
http://dx.doi.org/10.1242/dmm.037697

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451435/
https://www.ncbi.nlm.nih.gov/pubmed/30792270
http://dx.doi.org/10.1242/dmm.037697

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