Single cell analysis of clonal architecture in acute myeloid leukaemia

We used single cell Q-PCR on a micro-fluidic platform (Fluidigm) to analyse clonal, genetic architecture and phylogeny in acute myeloid leukaemia (AML) using selected mutations. Ten cases of NPM1c mutant AML were screened for 111 mutations that are recurrent in AML and cancer. Clonal architectures w...

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Detalles Bibliográficos
Autores principales: Potter, Nicola, Miraki-Moud, Farideh, Ermini, Luca, Titley, Ian, Vijayaraghavan, Gowri, Papaemmanuil, Elli, Campbell, Peter, Gribben, John, Taussig, David, Greaves, Mel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451634/
https://www.ncbi.nlm.nih.gov/pubmed/30568172
http://dx.doi.org/10.1038/s41375-018-0319-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451634/
https://www.ncbi.nlm.nih.gov/pubmed/30568172
http://dx.doi.org/10.1038/s41375-018-0319-2

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