Population Pharmacokinetics of Fludarabine in Children and Adults during Conditioning Prior to Allogeneic Hematopoietic Cell Transplantation

BACKGROUND: Fludarabine is often used as an important drug in reduced toxicity conditioning regimens prior to hematopoietic cell transplantation (HCT). As no definitive pharmacokinetic (PK) basis for HCT dosing for the wide age and weight range in HCT is available, linear body surface area (BSA)-bas...

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Detalles Bibliográficos
Autores principales: Langenhorst, Jurgen B., Dorlo, Thomas P. C., van Maarseveen, Erik M., Nierkens, Stefan, Kuball, Jürgen, Boelens, Jaap Jan, van Kesteren, Charlotte, Huitema, Alwin D. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451721/
https://www.ncbi.nlm.nih.gov/pubmed/30327943
http://dx.doi.org/10.1007/s40262-018-0715-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451721/
https://www.ncbi.nlm.nih.gov/pubmed/30327943
http://dx.doi.org/10.1007/s40262-018-0715-9

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