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Influences of sterol regulatory element binding protein-1c silencing on glucose production in HepG2 cells treated with free fatty acid

BACKGROUND: Elevation of exogenous free fatty acid (FFA) level leads to insulin resistance (IR) in liver, IR is manifested by elevated hepatic glucose production. We aim to study whether inhibition of endogenous fatty acid synthesis could decrease hepatic glucose production. METHODS: Low-passage Hep...

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Detalles Bibliográficos
Autores principales: Bai, Xiu-Ping, Dong, Feng, Yang, Guo-Hua, Zhang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451783/
https://www.ncbi.nlm.nih.gov/pubmed/30954075
http://dx.doi.org/10.1186/s12944-019-1026-3