Cargando…

Antiviral effects against influenza A virus infection by a short hairpin RNA targeting the non-coding terminal region of the viral nucleoprotein gene

RNA interference (RNAi) can inhibit Influenza A virus (IAV) infection in a gene-specific manner. In this study, we constructed a transgene expressing a short hairpin RNA (shRNA) that targets the noncoding region of the IAV RNA gene encoding nucleoprotein (NP). To investigate the antiviral effects of...

Descripción completa

Detalles Bibliográficos
Autores principales: FUJIMOTO, Yoshikazu, KYOGOKU, Kenji, TAKEDA, Keiko, OZAKI, Kinuyo, YAMAMOTO, Sayo, SUYAMA, Haruka, ONO, Etsuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451914/
https://www.ncbi.nlm.nih.gov/pubmed/30674743
http://dx.doi.org/10.1292/jvms.18-0436