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The Contribution of Low-Frequency and Rare Coding Variation to Susceptibility to Type 2 Diabetes
PURPOSE OF REVIEW: Soon after the first genome-wide association study (GWAS) for type 2 diabetes (T2D) was published, it was hypothesized that rare and low-frequency variants might explain a substantial proportion of disease risk. Rare coding variants in particular were emphasized given their large...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer US
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451938/ https://www.ncbi.nlm.nih.gov/pubmed/30957210 http://dx.doi.org/10.1007/s11892-019-1142-5 |