Higher serum galactose-deficient immunoglobulin A1 concentration is associated with stronger mesangial cellular inflammatory response and more severe histologic findings in immunoglobulin A nephropathy

BACKGROUND: Galactose-deficient immunoglobulin A1 (Gd-IgA1) is known to play a key role in the pathogenesis of IgA nephropathy (IgAN). We aimed to evaluate whether serum Gd-IgA1 is associated with in vitro activation of mesangial cells in individual patients and how this affects the clinical and his...

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Detalles Bibliográficos
Autores principales: Nguyen, Celine, König, Katrin, Tam, Frederick W K, Hopfer, Helmut, Molyneux, Karen, Binet, Francoise-Isabelle, Kim, Min Jeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Glomerulonephritis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6452211/
https://www.ncbi.nlm.nih.gov/pubmed/30976401
http://dx.doi.org/10.1093/ckj/sfy068

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6452211/
https://www.ncbi.nlm.nih.gov/pubmed/30976401
http://dx.doi.org/10.1093/ckj/sfy068

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