CRISPR-Cas immunity leads to a coevolutionary arms race between Streptococcus thermophilus and lytic phage

CRISPR-Cas is an adaptive prokaryotic immune system that prevents phage infection. By incorporating phage-derived ‘spacer’ sequences into CRISPR loci on the host genome, future infections from the same phage genotype can be recognized and the phage genome cleaved. However, the phage can escape CRISP...

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Detalles Bibliográficos
Autores principales: Common, Jack, Morley, Daniel, Westra, Edze R., van Houte, Stineke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6452269/
https://www.ncbi.nlm.nih.gov/pubmed/30905285
http://dx.doi.org/10.1098/rstb.2018.0098

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6452269/
https://www.ncbi.nlm.nih.gov/pubmed/30905285
http://dx.doi.org/10.1098/rstb.2018.0098

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