OR14I1 is a receptor for the human cytomegalovirus pentameric complex and defines viral epithelial cell tropism

A human cytomegalovirus (HCMV) pentameric glycoprotein complex (PC), gH–gL–UL128–UL130–UL131A, is necessary for viral infection of clinically relevant cell types, including epithelial cells, which are important for interhost transmission and disease. We performed genome-wide CRISPR/Cas9 screens of d...

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Detalles Bibliográficos
Autores principales: E, Xiaofei, Meraner, Paul, Lu, Ping, Perreira, Jill M., Aker, Aaron M., McDougall, William M., Zhuge, Ronghua, Chan, Gary C., Gerstein, Rachel M., Caposio, Patrizia, Yurochko, Andrew D., Brass, Abraham L., Kowalik, Timothy F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6452726/
https://www.ncbi.nlm.nih.gov/pubmed/30894498
http://dx.doi.org/10.1073/pnas.1814850116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6452726/
https://www.ncbi.nlm.nih.gov/pubmed/30894498
http://dx.doi.org/10.1073/pnas.1814850116

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