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Gene activation precedes DNA demethylation in response to infection in human dendritic cells

DNA methylation is considered to be a relatively stable epigenetic mark. However, a growing body of evidence indicates that DNA methylation levels can change rapidly; for example, in innate immune cells facing an infectious agent. Nevertheless, the causal relationship between changes in DNA methylat...

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Detalles Bibliográficos
Autores principales: Pacis, Alain, Mailhot-Léonard, Florence, Tailleux, Ludovic, Randolph, Haley E., Yotova, Vania, Dumaine, Anne, Grenier, Jean-Christophe, Barreiro, Luis B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6452747/
https://www.ncbi.nlm.nih.gov/pubmed/30886108
http://dx.doi.org/10.1073/pnas.1814700116