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The fitness cost and benefit of phase‐separated protein deposits

Phase separation of soluble proteins into insoluble deposits is associated with numerous diseases. However, protein deposits can also function as membrane‐less compartments for many cellular processes. What are the fitness costs and benefits of forming such deposits in different conditions? Using a...

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Detalles Bibliográficos
Autores principales: Sanchez de Groot, Natalia, Torrent Burgas, Marc, Ravarani, Charles NJ, Trusina, Ala, Ventura, Salvador, Babu, M Madan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6452874/
https://www.ncbi.nlm.nih.gov/pubmed/30962358
http://dx.doi.org/10.15252/msb.20178075