CD46 knock-out using CRISPR/Cas9 editing of hTERT immortalized human cells modulates complement activation

The kidney is especially sensitive to diseases associated with overactivation of the complement system. While most of these diseases affect kidney glomeruli and the microvasculature, there is also evidence for tubulointerstitial deposition of complement factors. Complement inactivating factors on ce...

Descripción completa

Detalles Bibliográficos
Autores principales: Wieser, Matthias, Francisci, Teresa, Lackner, Daniel, Buerckstuemmer, Tilmann, Wasner, Kamilla, Eilenberg, Wolf, Stift, Anton, Wahrmann, Markus, Böhmig, Georg A., Grillari, Johannes, Grillari-Voglauer, Regina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453361/
https://www.ncbi.nlm.nih.gov/pubmed/30958843
http://dx.doi.org/10.1371/journal.pone.0214514

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453361/
https://www.ncbi.nlm.nih.gov/pubmed/30958843
http://dx.doi.org/10.1371/journal.pone.0214514

Ejemplares similares