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Post-exposure administration of chimeric antibody protects mice against European, Siberian, and Far-Eastern subtypes of tick-borne encephalitis virus

Tick-borne encephalitis virus (TBEV) is the most important tick-transmitted pathogen. It belongs to the Flaviviridae family and causes severe human neuroinfections. In this study, protective efficacy of the chimeric antibody chFVN145 was examined in mice infected with strains belonging to the Far-Ea...

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Detalles Bibliográficos
Autores principales: Matveev, Andrey L., Kozlova, Irina V., Stronin, Oleg V., Khlusevich, Yana A., Doroshchenko, Elena K., Baykov, Ivan K., Lisak, Oksana V., Emelyanova, Ljudmila A., Suntsova, Olga V., Matveeva, Vera A., Savinova, Julia S., Tikunova, Nina V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453444/
https://www.ncbi.nlm.nih.gov/pubmed/30958863
http://dx.doi.org/10.1371/journal.pone.0215075