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An expanded variant list and assembly annotation identifies multiple novel coding and noncoding genes for prostate cancer risk using a normal prostate tissue eQTL data set

Prostate cancer (PrCa) is highly heritable; 284 variants have been identified to date that are associated with increased prostate cancer risk, yet few genes contributing to its development are known. Expression quantitative trait loci (eQTL) studies link variants with affected genes, helping to dete...

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Detalles Bibliográficos
Autores principales: DeRycke, Melissa S., Larson, Melissa C., Nair, Asha A., McDonnell, Shannon K., French, Amy J., Tillmans, Lori S., Riska, Shaun M., Baheti, Saurabh, Fogarty, Zachary C., Larson, Nicholas B., O’Brien, Daniel R., Cheville, John C., Wang, Liang, Schaid, Daniel J., Thibodeau, Stephen N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453468/
https://www.ncbi.nlm.nih.gov/pubmed/30958860
http://dx.doi.org/10.1371/journal.pone.0214588