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mRNA-Based Protein Replacement Therapy for the Heart
Myocardial infarction (MI) and heart failure (HF) are the leading causes of death in the United States and in most other industrialized nations. MI leads to a massive loss of cardiomyocytes (CMs), which are replaced with non-CM cells, leading to scarring and, in most cases, HF. The adult mammalian h...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453506/ https://www.ncbi.nlm.nih.gov/pubmed/30611663 http://dx.doi.org/10.1016/j.ymthe.2018.11.018 |