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Identification of pharmacodynamic biomarker hypotheses through literature analysis with IBM Watson

BACKGROUND: Pharmacodynamic biomarkers are becoming increasingly valuable for assessing drug activity and target modulation in clinical trials. However, identifying quality biomarkers is challenging due to the increasing volume and heterogeneity of relevant data describing the biological networks th...

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Detalles Bibliográficos
Autores principales: Hatz, Sonja, Spangler, Scott, Bender, Andrew, Studham, Matthew, Haselmayer, Philipp, Lacoste, Alix M. B., Willis, Van C., Martin, Richard L., Gurulingappa, Harsha, Betz, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453528/
https://www.ncbi.nlm.nih.gov/pubmed/30958864
http://dx.doi.org/10.1371/journal.pone.0214619