Increased dose of carbidopa with levodopa and entacapone improves “off” time in a randomized trial

OBJECTIVE: To investigate whether increased fixed carbidopa doses of 65 or 105 mg (ODM-101/65 and ODM-101/105) in combination with 75, 100, 125, or 150 mg of levodopa and 200 mg of entacapone might improve “off” time in fluctuating Parkinson disease (PD) compared to the standard combination of 4:1 l...

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Detalles Bibliográficos
Autores principales: Trenkwalder, Claudia, Kuoppamäki, Mikko, Vahteristo, Mikko, Müller, Thomas, Ellmén, Juha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453771/
https://www.ncbi.nlm.nih.gov/pubmed/30824559
http://dx.doi.org/10.1212/WNL.0000000000007173

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453771/
https://www.ncbi.nlm.nih.gov/pubmed/30824559
http://dx.doi.org/10.1212/WNL.0000000000007173

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