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Computational Prediction of MoRFs, Short Disorder-to-order Transitioning Protein Binding Regions

Molecular recognition features (MoRFs) are short protein-binding regions that undergo disorder-to-order transitions (induced folding) upon binding protein partners. These regions are abundant in nature and can be predicted from protein sequences based on their distinctive sequence signatures. This f...

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Detalles Bibliográficos
Autores principales: Katuwawala, Akila, Peng, Zhenling, Yang, Jianyi, Kurgan, Lukasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453775/
https://www.ncbi.nlm.nih.gov/pubmed/31007871
http://dx.doi.org/10.1016/j.csbj.2019.03.013