Highly Efficient and Selective CAR-Gene Transfer Using CD4- and CD8-Targeted Lentiviral Vectors

Chimeric antigen receptor (CAR)-modified T cells have revealed promising results in the treatment of cancer, but they still need to overcome various hurdles, including a complicated manufacturing process. Receptor-targeted lentiviral vectors (LVs) delivering genes selectively to T cell subtypes may...

Descripción completa

Detalles Bibliográficos
Autores principales: Jamali, Arezoo, Kapitza, Laura, Schaser, Thomas, Johnston, Ian C.D., Buchholz, Christian J., Hartmann, Jessica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453803/
https://www.ncbi.nlm.nih.gov/pubmed/30997367
http://dx.doi.org/10.1016/j.omtm.2019.03.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453803/
https://www.ncbi.nlm.nih.gov/pubmed/30997367
http://dx.doi.org/10.1016/j.omtm.2019.03.003

Ejemplares similares