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Angiotensin Receptor Neprilysin Inhibitor Attenuates Myocardial Remodeling and Improves Infarct Perfusion in Experimental Heart Failure

Angiotensin receptor blocker-neprilysin inhibitor (ARNi) therapy improves the prognosis of heart failure patients. However, the mechanisms remain unclear. This study investigated the biological effects of ARNi with neprilysin inhibitor sacubitril and angiotensin receptor blocker valsartan on myocard...

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Detalles Bibliográficos
Autores principales: Pfau, Daniel, Thorn, Stephanie L., Zhang, Jiasheng, Mikush, Nicole, Renaud, Jennifer M., Klein, Ran, deKemp, Robert A., Wu, Xiaohong, Hu, Xiaoyue, Sinusas, Albert J., Young, Lawrence H., Tirziu, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453892/
https://www.ncbi.nlm.nih.gov/pubmed/30962467
http://dx.doi.org/10.1038/s41598-019-42113-0