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Early endosome autoantigen 1 regulates IL-1β release upon caspase-1 activation independently of gasdermin D membrane permeabilization

Unconventional protein secretion represents an important process of the inflammatory response. The release of the pro-inflammatory cytokine interleukin (IL)-1β which burst during pyroptosis as a consequence of gasdermin D plasma membrane pore formation, can also occur through other unconventional se...

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Detalles Bibliográficos
Autores principales: Baroja-Mazo, Alberto, Compan, Vincent, Martín-Sánchez, Fátima, Tapia-Abellán, Ana, Couillin, Isabelle, Pelegrín, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453936/
https://www.ncbi.nlm.nih.gov/pubmed/30962463
http://dx.doi.org/10.1038/s41598-019-42298-4