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Early endosome autoantigen 1 regulates IL-1β release upon caspase-1 activation independently of gasdermin D membrane permeabilization
Unconventional protein secretion represents an important process of the inflammatory response. The release of the pro-inflammatory cytokine interleukin (IL)-1β which burst during pyroptosis as a consequence of gasdermin D plasma membrane pore formation, can also occur through other unconventional se...
Autores principales: | Baroja-Mazo, Alberto, Compan, Vincent, Martín-Sánchez, Fátima, Tapia-Abellán, Ana, Couillin, Isabelle, Pelegrín, Pablo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453936/ https://www.ncbi.nlm.nih.gov/pubmed/30962463 http://dx.doi.org/10.1038/s41598-019-42298-4 |
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