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Uncoupling of in-vitro identity of embryonic limb derived skeletal progenitors and their in-vivo bone forming potential
The healing of large bone defects remains a major unmet medical need. Our developmental engineering approach consists of the in vitro manufacturing of a living cartilage tissue construct that upon implantation forms bone by recapitulating an endochondral ossification process. Key to this strategy is...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453955/ https://www.ncbi.nlm.nih.gov/pubmed/30962493 http://dx.doi.org/10.1038/s41598-019-42259-x |