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Coordinated host-pathogen transcriptional dynamics revealed using sorted subpopulations and single macrophages infected with Candida albicans

The outcome of fungal infections depends on interactions with innate immune cells. Within a population of macrophages encountering Candida albicans, there are distinct host-pathogen trajectories; however, little is known about the molecular heterogeneity that governs these fates. Here we developed a...

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Detalles Bibliográficos
Autores principales: Muñoz, José F., Delorey, Toni, Ford, Christopher B., Li, Bi Yu, Thompson, Dawn A., Rao, Reeta P., Cuomo, Christina A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453965/
https://www.ncbi.nlm.nih.gov/pubmed/30962448
http://dx.doi.org/10.1038/s41467-019-09599-8