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Coordinated host-pathogen transcriptional dynamics revealed using sorted subpopulations and single macrophages infected with Candida albicans
The outcome of fungal infections depends on interactions with innate immune cells. Within a population of macrophages encountering Candida albicans, there are distinct host-pathogen trajectories; however, little is known about the molecular heterogeneity that governs these fates. Here we developed a...
Autores principales: | Muñoz, José F., Delorey, Toni, Ford, Christopher B., Li, Bi Yu, Thompson, Dawn A., Rao, Reeta P., Cuomo, Christina A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453965/ https://www.ncbi.nlm.nih.gov/pubmed/30962448 http://dx.doi.org/10.1038/s41467-019-09599-8 |
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