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BayesPI-BAR2: A New Python Package for Predicting Functional Non-coding Mutations in Cancer Patient Cohorts

Most of somatic mutations in cancer occur outside of gene coding regions. These mutations may disrupt the gene regulation by affecting protein-DNA interaction. A study of these disruptions is important in understanding tumorigenesis. However, current computational tools process DNA sequence variants...

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Detalles Bibliográficos
Autores principales: Batmanov, Kirill, Delabie, Jan, Wang, Junbai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454009/
https://www.ncbi.nlm.nih.gov/pubmed/31001324
http://dx.doi.org/10.3389/fgene.2019.00282