Contributions of Animal Models to the Mechanisms and Therapies of Transthyretin Amyloidosis

Transthyretin amyloidosis (ATTR amyloidosis) is a fatal systemic disease caused by amyloid deposits of misfolded transthyretin, leading to familial amyloid polyneuropathy and/or cardiomyopathy, or a rare oculoleptomeningeal amyloidosis. A good model system that mimic the disease phenotype is crucial...

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Detalles Bibliográficos
Autores principales: Ibrahim, Ridwan Babatunde, Liu, Yo-Tsen, Yeh, Ssu-Yu, Tsai, Jin-Wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454033/
https://www.ncbi.nlm.nih.gov/pubmed/31001136
http://dx.doi.org/10.3389/fphys.2019.00338

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454033/
https://www.ncbi.nlm.nih.gov/pubmed/31001136
http://dx.doi.org/10.3389/fphys.2019.00338

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