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Proviral Quasispecies Diversity Is Not Associated With Virologic Breakthrough or CD4(+) T Cell Loss in HIV-1 Elite Controllers
Elite controllers (EC) are able to control HIV-1 replication to extremely low levels (<50 HIV-1 RNA copies/mL) in the absence of antiretroviral therapy. However, some EC experience CD4(+) T cell loss and/or lose their ability to control HIV-1 over the course of infection. High levels of HIV-1 env...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454058/ https://www.ncbi.nlm.nih.gov/pubmed/31001238 http://dx.doi.org/10.3389/fmicb.2019.00673 |