Fluoro-Aryl Substituted α,β(2,3)-Peptides in the Development of Foldameric Antiparallel β-Sheets: A Conformational Study

α,β(2,3)-Disteroisomeric foldamers of general formula Boc(S-Ala-β-2R,3R-Fpg)(n)OMe or Boc(S-Ala-β-2S,3S-Fpg)(n)OMe were prepared from both enantiomers of syn H-2-(2-F-Phe)-h-PheGly-OH (named β-Fpg) and S-alanine. Our peptides show two appealing features for biomedical applications: the presence of f...

Descripción completa

Detalles Bibliográficos
Autores principales: Bucci, Raffaella, Contini, Alessandro, Clerici, Francesca, Beccalli, Egle Maria, Formaggio, Fernando, Maffucci, Irene, Pellegrino, Sara, Gelmi, Maria Luisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454073/
https://www.ncbi.nlm.nih.gov/pubmed/31001518
http://dx.doi.org/10.3389/fchem.2019.00192

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454073/
https://www.ncbi.nlm.nih.gov/pubmed/31001518
http://dx.doi.org/10.3389/fchem.2019.00192

Ejemplares similares