Cargando…
Fluoro-Aryl Substituted α,β(2,3)-Peptides in the Development of Foldameric Antiparallel β-Sheets: A Conformational Study
α,β(2,3)-Disteroisomeric foldamers of general formula Boc(S-Ala-β-2R,3R-Fpg)(n)OMe or Boc(S-Ala-β-2S,3S-Fpg)(n)OMe were prepared from both enantiomers of syn H-2-(2-F-Phe)-h-PheGly-OH (named β-Fpg) and S-alanine. Our peptides show two appealing features for biomedical applications: the presence of f...
Autores principales: | Bucci, Raffaella, Contini, Alessandro, Clerici, Francesca, Beccalli, Egle Maria, Formaggio, Fernando, Maffucci, Irene, Pellegrino, Sara, Gelmi, Maria Luisa |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454073/ https://www.ncbi.nlm.nih.gov/pubmed/31001518 http://dx.doi.org/10.3389/fchem.2019.00192 |
Ejemplares similares
-
Non-natural 3-Arylmorpholino-β-amino
Acid as a PPII Helix Inducer
por: Vaghi, Francesco, et al.
Publicado: (2020) -
The extent of protein hydration dictates the preference for heterogeneous or homogeneous nucleation generating either parallel or antiparallel β-sheet α-synuclein aggregates
por: Camino, José D., et al.
Publicado: (2020) -
Rationally designed foldameric adjuvants enhance antibiotic efficacy via promoting membrane hyperpolarization
por: Bhaumik, Kaushik Nath, et al.
Publicado: (2021) -
The Functional Mammalian CRES (Cystatin-Related Epididymal Spermatogenic) Amyloid is Antiparallel β-Sheet Rich and Forms a Metastable Oligomer During Assembly
por: Do, Hoa Quynh, et al.
Publicado: (2019) -
Ultrashort Peptides and Gold Nanoparticles: Influence of Constrained Amino Acids on Colloidal Stability
por: Locarno, Silvia, et al.
Publicado: (2021)