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Antithrombotic Effect of shRNA Target F12 Mediated by Adeno-Associated Virus

Coagulation factor XII (FXII) plays a crucial role in thrombosis. Moreover, deficiencies in FXII are not associated with excessive bleeding, and its depletion exhibits satisfactory protective effect on thrombus formation. Several strategies targeting FXII have been applied to inhibit thrombosis form...

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Detalles Bibliográficos
Autores principales: Li, Fanfan, Yang, Xiao, Liu, Jie, Shu, Kuangyi, Shen, Chenfang, Chen, Tao, Yang, Wei, Li, Shanshan, Wang, Xiaoou, Jiang, Minghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454094/
https://www.ncbi.nlm.nih.gov/pubmed/30959404
http://dx.doi.org/10.1016/j.omtn.2019.02.026