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Radiotherapy Both Promotes and Inhibits Myeloid-Derived Suppressor Cell Function: Novel Strategies for Preventing the Tumor-Protective Effects of Radiotherapy

Cancer immunotherapies aimed at neutralizing the programmed death-1 (PD-1) immune suppressive pathway have yielded significant therapeutic efficacy in a subset of cancer patients. However, only a subset of patients responds to antibody therapy with either anti-PD-1 or anti-PD-L1 antibodies. These pa...

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Detalles Bibliográficos
Autores principales: Ostrand-Rosenberg, Suzanne, Horn, Lucas A., Ciavattone, Nicholas G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454107/
https://www.ncbi.nlm.nih.gov/pubmed/31001479
http://dx.doi.org/10.3389/fonc.2019.00215