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Antenatal Hypoxia and Programming of Glucocorticoid Receptor Expression in the Adult Rat Heart

Glucocorticoid receptor (GR) signaling is critical for development and function of the heart. Our previous study demonstrated that gestational hypoxia induced epigenetic repression of the GR gene in the developing heart. The present study aims to determine that the alterations of promoter methylatio...

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Detalles Bibliográficos
Autores principales: Lv, Juanxiu, Ma, Qingyi, Dasgupta, Chiranjib, Xu, Zhice, Zhang, Lubo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454194/
https://www.ncbi.nlm.nih.gov/pubmed/31001129
http://dx.doi.org/10.3389/fphys.2019.00323